Internships at PSC

Internship positions at PSC are an opportunity for students to grow and learn in a supportive environment with world-class mentors.

Focus areas include:

- Systems and Operations
- Cybersecurity
- Computational Science
- Research Support Services
- Bioinformatics
- Artificial Intelligence & Machine Learning
- Data Curation
- Marketing & Communications
- Project Management

Program Details:

12 weeks
35 hours per week
1:1 mentorship
Shadowing opportunities to learn about HPC with PSC staff
Hybrid work posture

Positions are posted at the start of January.

Applications close at the end of February.

Apply Today!

Check out our careers page for more details and current open internships.

PSC Interns to Represent U.S. at International Student Competition

Benchmark Beasts Team to Compete at ISC25 Conference in Hamburg, Germany

Coming Soon

See below for a preview of our internship postings that will be open for applications in January 2025.

Neocortex Internship with PSC’s AI & Big Data Team

PSC’s Neocortex offers the Cerebras wafer scale engine (WSE) to drastically accelerate the training of transformer models. Recently, these models have been applied to materials science and chemistry for property prediction. In this project, we leverage the computational power of the WSE to examine three recently developed string representations for organic molecular crystals in relation to predicting the bandgap property. We pre-train the RoBERTa transformer model on Neocortex and then train a regression head on NVIDIA GPUs available on PSC’s Bridges-2. Applicants with interest in chemistry and materials science are preferred, especially those with experience in structural libraries such as Pymatgen and ASE.

Monte Carlo Methods for Simulating Microphysiology, Internship with PSC’s Biomedical Team

Abstract: Computational modeling is becoming very important in different fields of science. The ability to use modeling and simulation is a core competency that many undergraduate students need to develop. New technology and computational approaches permit modeling of increasingly complicated biological systems. For example, the cell modeling software MCell uses Monte Carlo algorithms to track the evolution of biochemical events in space and time for individual molecules. Details about molecular structures are ignored. Particles move according to a 3D Brownian-dynamics random walk and encounter boundaries and surface molecules as they diffuse which may result in chemical reactions governed by user specified mechanisms. As a case study we use MCell software to provide insight into many experimentally inaccessible aspects of synaptic function and the microscopic mechanisms underlying Ca2+ triggered synaptic vesicle release. The stochastic computational modeling using MCell can also be used to model and evaluate a novel treatment for Lambert-Eaton Myasthenic Syndrome (LEMS), a neuromuscular disease that is characterized by motor nerve terminal weakness. This neurological disease is known to disrupt the normally well-organized active zone (AZ) and reduce the number of presynaptic calcium channels. This autoantibody mediated reduction of presynaptic calcium channels leads to severe muscle weakness.

Learning Focus: Students will learn the basics of CellBlender and MCell. The mouse MCell models of neuromuscular junction, and synaptic vesicle release mechanism. In collaboration with Dr. Steve Meriney (Neuroscience Dept., University of Pittsburgh) and Dr. Robert E Poage (Professor Of Biology at University of North Carolina at Pembroke) they will study the effects of varying the spatial distribution of the voltage-gated Ca2+ channels (VGCCs), stochastic Ca2+ influx, diffusion, and binding on synaptic function. The students will learn how to use supercomputers and how to analyze and interpret the output of simulations. Finally, we will work on the molecular issues underlying the neuromuscular diseases and age-induced loss of muscle strength. The students will use a previously validated MCell computer simulation model of mammalian neuromuscular junction (NMJ) active zones (AZs) to alter VGCC density and distribution, number of vesicles, and other parameters, and determine if these changes in the AZ, can predict synaptic function measured by our collaborators.

Bridges-2 Internship

PSC staff prepare a large number of scientific software packages for use by researchers on Bridges-2. The diversity of installation methods and individual preferences has established a complex mix of software management strategies, leading to duplicated effort in preparing new and updated packages, inconsistent deployment across multiple kinds of compute nodes, and many other behind-the-scenes issues. Recent efforts have implemented a new package management framework to organize these software packages into a single coherent system. This internship will involve refinining this package management framework and extending it to incorporate additional features such as regression testing, collection of usage metrics, and integration with external tools which track software deployments and availability. Successful applicants will need familiarity with Python, Bash, and the Linux/Unix command line, and a strong ability to learn independently by studying software documentation.