by Ken Chiacchia | Apr 7, 2025 | Anton, Anton 2, Science Highlights
Adobe Stock 508244320 “Tucking In” of Viral Capsid Protein Allows Passage of Giant Structure through Nuclear Pore, Allowing Virus to Take Over The hepatitis B virus causes about 800,000 deaths per year, on par with HIV and the malaria parasite. However, as it spreads,...
by Ken Chiacchia | Oct 22, 2024 | Anton, Anton 2, Research, Science Highlights
With Alzheimer’s disease, amyloid peptides combine to form fibrils, in turn forming plaques around neurons. Adobe Stock 421239213 Unexpected Way for Amyloid Peptides to Join Fibrils Explains Time Lag, then Accelerated Growth, in Fibril Formation and Disease...
by Ken Chiacchia | Jul 31, 2024 | Anton, Anton 2, Research, Science Highlights
Scientists used the second-generation DESRES Anton supercomputer hosted at PSC to show how a critical protein for furture gene therapy pauses before completing its cutting of a target DNA. Credit: Aakash Saha Understanding Unexpected Motion of Protein Will Be Crucial...
by Ken Chiacchia | Jun 3, 2024 | Anton 2, Research, Science Highlights
This image shows the complexity of simulating the functional movements of the voltage-sensitive phosphatase’s motions. Anton 2 enables scientists to reproduce the movements of the protein’s components, as well as the lipids (grey, with the headgroups colored), water...
by Ken Chiacchia | Jun 8, 2023 | Anton 2, Science Highlights
Snapshot of the β2AR–Gs system: NE(+)-bound β2AR coupled with Gs protein. Different subunits and loops are illustrated by different colors (Green – β2AR, Gray – intracellular loop 3 or ICL3, Pink – GsαAH domain, Red – GsαRas domain, Blue – Gβ, Yellow – Gγ). From Y....
by Ken Chiacchia | Mar 1, 2023 | Anton 2, Science Highlights
Comparison of where D-serine (D-Ser, teal dots) and glutamate (Glu, gray dots) stick to the GluN2AA subunit. From Remy A Yovanno Tsung Han Chou Sarah J Brantley Hiro Furukawa Albert Y Lau (2022) Excitatory and inhibitory D-serine binding to the NMDA receptor eLife...