Pittsburgh Supercomputing Center 

Advancing the state-of-the-art in high-performance computing,
communications and data analytics.


Computational Modules in Science Teaching (CMIST) brings innovative science tutorials into secondary school classrooms, focusing on integrative computational biology, physiology, and biophysics. CMIST modules include high quality, realistic 3-D animations produced with cutting-edge simulation and visualization software.
CMIST subject material is chosen to highlight critical concepts that are difficult to convey with static textbook images and words; for example, cellular transport of molecules by diffusion and osmosis, or the structure and function of enzymes in cells. Specific modules are introduced in two-hour workshops throughout the school year.  
3-D Animations

An Introduction to Enzymes

Enzyme Kinetics

The Effect of Temperature on Enzyme Catalysis



Principles of Diffusion and Molecular Flux

Diffusion Time and Distance: Cellular vs. Desktop Diffusion

Diffusion Time and Distance: Glucose Molecules vs. Sodium Ions

Brownian Motion in Water

Big Numbers in Small Spaces



Osmosis and its Effects on Red Blood Cell Volume

Osmosis: Osmotic vs. Hydrostatic Pressure



Neuromuscular Transmission and slow Channel Congental Myasthenic Syndrome

Neuromuscular Junction 1

3D Reconstruction of Nerve-Muscle Synapse

24 Active Zones



Birth of a Protein

Lotka-Volterra Reaction

Single Channel


CMIST is a program of the Biomedical Applications Group at Pittsburgh Supercomputing Center.